Clinical analysis of myoepithelial carcinoma of head and neck
10.3760/cma.j.issn.1673-0860.2010.02.009
- VernacularTitle:头颈部肌上皮癌临床分析
- Author:
Chun-Qiao LI
1
;
Zhu-Ming GUO
;
Wei-Wei LIU
;
Quan ZHANG
;
An-Kui YANG
;
Lei YANG
Author Information
1. 中山医科大学附属肿瘤防治中心
- Keywords:
Head and neck neoplasms;
Myoepithelioma;
Neoplasm metastasis
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2010;45(2):124-127
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate clinical feature, diagnosis, treatment and prognosis of myoepithelial carcinoma (MC) in the head and neck.Methods Clinical data of 11 patients which were confirmed by pathology and immunohistochemistry in Cancer Center, Sun Yat-sen University from Jan.1992 to Dec.2006, were reviewed.There were 5 cases in parotid gland, 1 in hard palate, 1 in maxillary sinus , 1 in pharyngeal recess, 1 in bucca cavioris, 1 in scalp, and 1 in gingiva.Male to female ratio was 4 to 7.The median age at diagnosis was 37 years (range:14-60 years).Results All cases were operated,4 underwent surgery alone,2 underwent surgery plus adjuvant radiotherapy,2 received surgery plus adjuvant chemotherap, 3 underwent surgery plus adjuvant chemoradiation.After operation, 8 cases occurred local recurrence and 4 cases occurred distance and lymph nodes metastasis.There was spindle cell type in 5 cases, clear cell type, plasmacytoid cell type in 2 cases, epithelioid cell type, mixed type in 1 case.The median follow-up time was 40 months. Eight patients died of tumar until the last follow-up, while 3 patients lived.Conclusions The characteristic of the tumor was very aggressive, invading the surrounding regions, high rates of lymph node metastasis and high rates of distance metastasis.It was easily recurrence if the surgical excision was not radically for MC, and the prognosis was poorly.MC was a sort of high malignant tumor.Radical operation must be advocated initially.Chemotherapy and radiotherapy may be effective after operation.
