Factor analysis model for studying the influence of psychological stress on the endocrine network of reproduction axis.
- Author:
Laicheng LUO
1
;
Jianhong WANG
;
Na MA
;
Haiyun LIU
;
Minzhang WANG
Author Information
1. School of Basic Courses, Guangdong Pharmaceutical University, Guangzhou 510006, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Estradiol;
blood;
physiology;
Female;
Follicle Stimulating Hormone;
blood;
physiology;
Gonadotropin-Releasing Hormone;
blood;
physiology;
Models, Biological;
Neurosecretory Systems;
physiology;
Rats;
Reproduction;
physiology;
Stress, Psychological;
metabolism;
physiopathology;
beta-Endorphin;
blood;
physiology
- From:
Journal of Biomedical Engineering
2008;25(6):1368-1371
- CountryChina
- Language:Chinese
-
Abstract:
In order to explore the influence of psychological stress on the reproductive axis, we started with the original data of biology from animal experiments, then we conducted the factor analysis of 6 important bio-regulatory factors and established the Factor Analysis Model for the endocrine network of reproduction axis under psychological stress. Based on the biological data obtained from animal experiments, it is found that, compared with the relationship seen in the factor analysis model in normal condition, the relationship among the biological factors is more complicated. The key factor, GnRH, has lost its strong regulating action on the subordinate factors, especially on E2; on the other hand, beta-EP has very strong regulating action on E2, and E2 is controlled mainly by beta-EP.
