The studies on clinical value of AFP-L3 detected by microspincolum method for judgment of treatment response in patients with HCC undergoing TACE.
- Author:
Xiang ZHOU
1
;
Hong-ming PAN
;
Gong-ying CHEN
;
Meng-fei ZHU
;
Xiong-ying ZHU
;
Jie WANG
;
Bai-lu REN
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Carcinoma, Hepatocellular; chemistry; therapy; Chemoembolization, Therapeutic; methods; Female; Humans; Liver Neoplasms; chemistry; therapy; Male; Middle Aged; Treatment Outcome; alpha-Fetoproteins; analysis
- From: Chinese Journal of Experimental and Clinical Virology 2013;27(1):61-63
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the clinical value of Lens culinaris agglutinin-reactive alpha-fetoprotein detected by microspincolum method for judgment of treatment response in patients with hepatocellular carcinoma undergoing transcatheter arterial chemoembolization.
METHODSTwenty eight patients with HCC undergoing TACE follow-up in hospital were recruited. AFP and AFP-L3 were measured in all the patients before and after TACE, and correlations were analyzed between AFP-L3% and response to treatment.
RESULTSAmong the twenty eight patients with HCC undergoing TACE, 8 out 11 case in AFP-L3% descent group had well treatment response, 5 out 17 case in AFP-L3% elevated group had well treatment response(Chi2 = 4. 858, P < 0. 05).
CONCLUSIONSThe detection of AFP-L3 by microspincolum method is useful to judgment of treatment response in patients with HCC undergoing TACE.
