The studies on clinical value of AFP-L3 detected by microspincolum method for judgment of treatment response in patients with HCC undergoing TACE

VernacularTitle:离心柱法检测甲胎异质体在预测TACE术后疗效的研究
Author: Xiang ZHOU ¹ ; Hong-Ming PAN ; Gong-Ying CHEN ; Meng-Fei ZHU ; Xiong-Ying ZHU ; Jie WANG ; Bai-Lu REN
Author Information

1. 浙江大学医学院附属邵逸夫医院肿瘤内科
Keywords: Alpha-fetoproteins; Carcinoma,hepatocellular
From: Chinese Journal of Experimental and Clinical Virology 2013;27(1):61-63
CountryChina
Language:Chinese
Abstract: Objective To explore the clinical value of Lens culinaris agglutinin-reactive alphafetoprotein detected by microspincolum method for judgment of treatment response in patients with hepatocellular carcinoma undergoing transcatheter arterial chemoembolization.Methods Twenty eight patients with HCC undergoing TACE follow-up in hospital were recruited.AFP and AFP-L3 were measured in all the patients before and after TACE,and correlations were analyzed between AFP-L3％ and response to treatment.Results Among the twenty eight patients with HCC undergoing TACE,8 out 11 case in AFP-L3％ descent group had well treatment response,5 out 17 case in AFP-L3％ elevated group had well treatment response(x2 =4.858,P ＜ 0.05).Conclusions The detection of AFP-L3 by microspincolum method is useful to judgment of treatment response in patients with HCC undergoing TACE.