Molecular and epidemiological study of human adenovirus among infants with diarrhea in Nanjing
10.3760/cma.j.issn.1003-9279.2013.03.003
- VernacularTitle:南京地区腹泻患儿腺病毒感染的分子流行病学研究
- Author:
Wen-Juan GAO
1
;
Xiao-Le LI
;
Na LIU
;
Zhao-Jun DUAN
;
Yu JIN
Author Information
1. 730000,兰州大学第一医院
- Keywords:
Adenoviridae;
Infant care;
Diarrhea;
Epidemiology
- From:
Chinese Journal of Experimental and Clinical Virology
2013;27(3):167-169
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the prevalence,clinic features and epidemiologic characteristics of human adenovirus diarrhea in Nanjing.Methods 730 stool specimens were collected from children with diarrhea in Nanjing Children's Hospital of Nanjing Medical University from June 2009 to June 2011.Polymerase chain reaction (PCR) was employed to detect human adenovirus.The total positive PCR products were typed by nest-PCR or multiple PCR.Results 21 samples (21/730) were positive for human adenovirus of all 730 samples from June 2009 to June 2011 and enteric HAdV-41 is the predominant stain.Conclusion Enteric HAdV-41 and non-enteric adenovirus were the major etiological agents of viral diarrhea among infants and children in Nanjing from 2009 to 2011.We should take the long-term systematic surveillance seriously.