Sero-epidemiological analysis for entervirus 71 infection of adults in Beijing.
- Author:
Jing-Jing WANG
1
;
Wei WU
;
Hui-Jie PAN
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Age Factors; Antibodies, Neutralizing; blood; Antibodies, Viral; blood; China; Enterovirus A, Human; immunology; isolation & purification; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoglobulin G; blood; Male; Middle Aged
- From: Chinese Journal of Experimental and Clinical Virology 2013;27(3):170-172
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the enterovirus 71 (EV 71) protective antibody level of health adults people in Beijing.
METHODSSerum samples and information of participants were collected from hospitals in Beijing. EV71 IgG was tested by enzyme-linked immunoadsordent assay (ELISA). EV 71 neutralization antibody was evaluated by micro-cytopathic effect neutralization test (MCPENT).
RESULTS486 participants were enrolled. Age range was 19-62 years old. The average EV 71 IgG positive rate was 40. 3% , there are no significant difference between the EV 71 IgG positive rate of male and female. The rate of EV 71 neutralization antibody which title high than 1:256 is 13.3%. The rate of EV 71 IgG and the titile of EV 71 neutralization antibody are decreasing by the age.
CONCLUSION40% of health adults of Beijing area have EV71 protective antibody. But the title higher than 1:256 is only 13.3%. EV 71 protective antibody decreases significantly with the age.
