To explore the safety testing evaluation index of breast-feeding by hepatitis B-positive mothers.
- Author:
Wen-Ping ZHANG
1
;
He-Ying SHI
;
Cai-Bin LI
;
Qi-Hong LI
;
Peng DU
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Breast Feeding; DNA, Viral; analysis; Female; Hepatitis B; virology; Hepatitis B e Antigens; analysis; Humans; Milk, Human; virology; Pregnancy; Pregnancy Complications, Infectious; virology
- From: Chinese Journal of Experimental and Clinical Virology 2013;27(3):202-203
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the safety testing evaluation index of breast-feeding by hepatitis B-positive mothers.
METHODSHBV DNA from serum and breast milk of 252 hepatitis B-positive mothers were detected with the real-time quantitative PCR.
RESULTSThe total positive rate of HBV DNA in serum had no difference with that in breast milk in hepatitis B-positive mothers (P > 0.05). The positive rate of HBV DNA in serum and breast milk of positive HBeAg were significantly higher than that of hepatitis B-positive mothers with negative HBeAg (P < 0.01).
CONCLUSIONTo detecte HBeAg and HBV DNA in serum and breast milk have important significance for guiding of breast feeding of hepatitis B-positive mothers.
