Risk Factors for Dry Eye in Thyroid-Associated Ophthalmopathy.
10.3341/jkos.2011.52.7.771
- Author:
Jae Ryun KIM
1
;
Hye Bin YIM
;
Sung Kun CHUNG
Author Information
1. Department of Ophthalmology and Visual Science, College of Medicine, The Catholic University of Korea, Seoul, Korea. eyedoc@catholic.ac.kr
- Publication Type:Original Article
- Keywords:
Dry eye syndrome;
Risk factors;
Thyroid-associated ophthalmopathy
- MeSH:
Dry Eye Syndromes;
Exophthalmos;
Eye;
Eye Diseases;
Eyelids;
Graves Ophthalmopathy;
Humans;
Logistic Models;
Retrospective Studies;
Risk Factors;
Tears;
Thyroid Gland
- From:Journal of the Korean Ophthalmological Society
2011;52(7):771-776
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To investigate the risk factors for dry eye in thyroid-associated ophthalmopathy patients. METHODS: The present retrospective study was conducted on 78 eyes in 39 patients diagnosed with thyroid-associated ophthalmopathy. The risk factors for dry eye in thyroid-associated ophthalmopathy patients were examined by analyzing data including tear break-up time, Schirmer's test, age, gender, thyroid function status, palpebral fissure width, lagophthalmos, eyelid retraction, and exophthalmos through multiple logistic regression analysis. RESULTS: The risk factors for dry eye disease were palpebral fissure width (OR = 3.422, p = 0.022) and lagophthalmos (OR = 13.068, p = 0.049). Age, gender, thyroid hormone status, eyelid retraction and exophthalmos did not show significant association with dry eye in multiple logistic regression analysis. The only risk factor for tear film break-up time less than 10 seconds was palpebral fissure width (OR = 2.787, p = 0.045), and none of the risk factors for Schirmer's test less than 10 mm at 5 minutes were statistically significant. CONCLUSIONS: Risk factors for dry eye in thyroid ophthalmopathy patients were palpebral fissure width and lagophthalmos.
