Lymph node metastasis in early gastric cancer.

Rong Chen; Qingsheng HE; Jianxin Cui; Shibo Bian; Lin Chen

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Lymph node metastasis in early gastric cancer.

Author: Rong CHEN ^{1
,

2} ; Qingsheng HE ¹ ; Jianxin CUI ³ ; Shibo BIAN ¹ ; Lin CHEN ¹ ;
Author Information

1. Department of General Surgery, Chinese People's Liberation Army General Hospital, Beijing 100853, China
2. School of Medicine, Nankai University, Tianjin 300071, China.
3. Department of General Surgery, Chinese People's Liberation Army General Hospital, Beijing 100853, China.
Publication Type:Journal Article
MeSH: Female; Humans; Lymphatic Metastasis; Male; Stomach Neoplasms; complications; pathology; surgery
From: Chinese Medical Journal 2014;127(3):560-567
CountryChina
Language:English
Abstract:
OBJECTIVETo discuss the clinicopathological factors for lymph node metastasis (LNM) in early gastric cancer (EGC), including age, gender, location, size, macroscopic type, depth of invasion, histological type, and lymphatic invasion, and the regulation of LNM in EGC.
DATA SOURCESThe data used in this review were mainly from PubMed articles published in English. The search terms were "early gastric cancer" and "lymph node metastasis".
STUDY SELECTIONArticles were selected if they reported the clinicopathological factors and regulation of LNM in EGC.
RESULTSThe prognosis of EGC is better than advanced gastric cancer, with over 90% 5-year survival rate. The main risk factors for LNM in EGC are tumor size, macroscopic type, depth of invasion, histological type, ulceration, and lymphatic invasion.
CONCLUSIONSLNM in EGC is a critical factor for assessment of prognosis and determination of therapeutic strategy. Endoscopic mucosal resection or endoscopic submucosal dissection should be considered when patients have low risk of LNM.