Pathological features and clinical managements of nasopharyngeal angiofibroma
10.3321/j.issn:1673-0860.2008.10.009
- VernacularTitle:鼻咽血管纤维瘤的病理特征和临床处理的探讨
- Author:
Chang LIN
1
;
Zhi-Chun LI
;
Jin-Mei CHENG
;
Gong-Biao LIN
;
Ai-Dong ZHOU
;
Zi-Xiang YI
Author Information
1. 福建医科大学附属第一医院(福建省耳鼻咽喉研究所)
- Keywords:
Nasopharyngeal neoplasms;
Angiofibroma;
Pathology
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2008;43(10):763-766
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the pathological features of nasopharyngeal angiofibroma (NA) and the principles for clinical managements. Methods Thirty-five patients with NAs were treated in First Affiliated Hospital of Fujian Medical University from Oct. 1981 to May 2007. The pathological changes, sites of origin, causes of intraoperative bleeding and the experiences of managements were retrospectively analysed. Using Fish stnge:6 cases were in stage Ⅰ ,8 cases were in stage Ⅱ,17 cases were in stage Ⅲ, 4 cases were stage Ⅳ. Two cases via endoscopic surgery,2 cases via palatal approach,19 cases via midfacial degloving approach, 9 cases via lateral rhinotomy approach, 3 cases via craniofacial combined approach. Results In nasal cavity and paranasal sinus, the tumor was covered by squamous or colummar epithelium. The tumor extensions such as in pterygopalatine fossa and infratemporal fossa were covered by fibrous pseudocapsule. All cases of this series originated in the lateral wall of posterior portion of the nasal cavity. Fifteen of thirty-five cases confidentially originated near sphenopalatine foramen. Large and thick vessels in the pedicle region were the exact sites of serious intraoperative bleeding. Thirty-one cases were totally removed. Four cases were subtotal resected. Visual less revealed in 6 cases, 4 cases visual acuity improved postoperatively. Three cases revealed postoperative dry eye due to surgical involvement of the sphenopalatine ganglion. Conclusions nasopharyngeal angiofibroma is covered by epithelium or pseudo-capsule, it does not infiltrate the surrounding tissue. Dissecting along the surface of tumor might decrease bleeding and facilitate removal of tumor. An ideal surgical management should be done according to actually size and image examination, to the greatest extent keeping normal facial appearance. Attention should be paid to the complications such as visual loss and dry eye.
