Change on burden of diseases from hypercholesterolemia among the Chinese population from 1990 to 2010.

Mingbo Liu; Wen Wang; Liyuan MA; Maigeng Zhou; Email: Maigengzhou@126com

Return

Change on burden of diseases from hypercholesterolemia among the Chinese population from 1990 to 2010.

Author: Mingbo LIU ¹ ; Wen WANG ¹ ; Liyuan MA ¹ ; Maigeng ZHOU ² ; Email: MAIGENGZHOU@126.COM.
Author Information

1. National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
2. National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China
Publication Type:Journal Article
MeSH: Asian Continental Ancestry Group; China; Disabled Persons; Female; Humans; Hypercholesterolemia; Male; Quality-Adjusted Life Years; Risk Factors; Stroke
From: Chinese Journal of Cardiology 2015;43(9):802-805
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo quantify the change on burden of disease from hypercholesterolemia in China from 1990 to 2010.
METHODSRelated data were obtained from the Global Burden of Diseases, Injuries, and Risk Factors Study 2010 (GBD 2010). Population attributable risk was adopted to estimate the burden of disease from hypercholesterolemia.
RESULTSThe death and burden of disease from hypercholesterolemia for Chinese residents increased from 98 000 and 2.237 million disability-adjusted of life years (DALY) in 1990 to 281 000 and 5.912 million DALY respectively. In 2010, 251 000 ischemic heart disease and 30 000 ischemic stroke deaths were caused by hypercholesterolemia, accounted for 3.4% (28.1/830.2) of the total deaths. In 2010, the DALY of ischemic heart disease and ischemic stroke attributed to hypercholesterolemia was 5.169 million and 0.743 million respectively. DALY was 3.356 million in male and 2.555 million in female. Years of life lost due to premature mortality (YLL) was 5.268 million, and years lived with disability (YLD) was 0.644 million.
CONCLUSIONHypercholesterolemia is a major risk factor for deaths and life loss in 2010, and the burden of disease and death from hypercholesterolemia increased obviously from 1990 to 2010 in China.