Uterine Leiomyoma with Massive Lymphocytic Infiltration.
- Author:
Won Mi LEE
1
;
Moon Hyang PARK
Author Information
1. Department of Pathology, Hanyang University College of Medicine, Seoul, Korea. parkmh@hanyang.ac.kr
- Publication Type:Case Report
- Keywords:
Uterine leiomyoma;
Lymphocytes;
B-lymphocytes
- MeSH:
B-Lymphocytes;
Female;
Gonadotropin-Releasing Hormone;
Histiocytes;
Humans;
Hysterectomy;
Korea;
Leiomyoma*;
Lymphocytes;
Middle Aged;
Phenotype;
Plasma Cells;
T-Lymphocytes
- From:Korean Journal of Pathology
2003;37(1):71-73
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Uterine leiomyoma with massive lymphocytic infiltration is known to be associated with Gona-dotropin releasing hormone (GnRH) agonist treatment. The lymphocytic cells in those cases were composed predominantly of T-lymphocytes. We report an unusual case of uterine leiomyoma with massive lymphocytic infiltration, composed predominantly of B-lymphocytes, without a history of GnRH agonist treatment. A 59-year-old woman underwent a transvaginal hysterectomy for uterine leiomyomas. Microscopically, the leiomyoma showed a massive infiltration of the lymphocytes, histiocytes, and also showed scattered plasma cells and many lymphoid follicles. The lymphocytic infiltrates were confined to the leiomyoma. These lymphocytic cells mainly represented the B-cell phenotype. She had no history of GnRH agonist treatment. To the best of our knowledge, This is the first reported case in Korea.
