Clinical features of recurrent Kawasaki disease in 20 children.
- Author:
Li-Xia ZOU
1
;
Fang-Qi GONG
Author Information
- Publication Type:Journal Article
- MeSH: Child; Child, Preschool; Coronary Artery Disease; etiology; Female; Humans; Immunoglobulins, Intravenous; therapeutic use; Infant; Male; Mucocutaneous Lymph Node Syndrome; complications; drug therapy; Recurrence; Retrospective Studies
- From: Chinese Journal of Contemporary Pediatrics 2008;10(5):617-619
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the clinical features of recurrent Kawasaki disease (KD) and the relationship of recurrent KD with coronary artery lesions.
METHODSThe medical data of 20 children with recurrent KD who were admitted to the Children's Hospital from January 1998 to May 2007 were retrospectively studied. Their clinical features were compared with those of children with initial KD.
RESULTSThe incidence of recurrent KD was 1.34% (20/1489). KD relapsed 2 months to 4.6 years (average: 1.2 years) after the first episode in the 20 children. Compared with the initial KD group, the clinical symptoms in the recurrent KD group were incomplete, complicated and less severe. The period of fever, platelet count, C-reactive protein and ESR were remarkably reduced in the recurrent KD group, but the incidence of coronary artery lesions increased significantly compared with the initial KD group (40% vs 25%; P<0.05).
CONCLUSIONSThe clinical symptoms of recurrent KD were incomplete in children. Recurrent KD was associated with an increased incidence of coronary artery lesions.