Expression of S-phase kinase associated protein 2 in laryngeal carcinoma anti its molecular mechanisms involved in regulation of proliferation and apoptosis of Hep-2 cells

VernacularTitle:S期激酶相关蛋白2在喉癌组织中的表达及调控增殖和凋亡的机制
Author: Xiu-Ying LU ¹ ; Xiao-Ming LI
Author Information

1. 白求恩国际和平医院
Keywords: RNA interference; Laryngeal neoplasms; Carcinoma; squamous cell; S-phase kinase-associated protein; Cylin-dependent kinase inhibitor
From: Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2009;44(8):681-686
CountryChina
Language:Chinese
Abstract: inoma. Silencing of Skp2 expression could inhibit cell proliferation and increase cell apoptosis in Hep-2 cells which might be related to the werease of p27 protein level and Sphase cell cycle arrest of Hep-2 cell.