Simultaneous liver-pancreas-duodenum transplantation: one case report and review of the literature.
- Author:
Jian XU
1
;
Li-xin YU
;
Wen-feng DENG
;
Shao-jie FU
;
Chuan-fu DU
;
Yi-bin WANG
;
Xiao-you LIU
;
Yun MIAO
;
Chuan-jiang LI
;
Jun-sheng YE
Author Information
- Publication Type:Case Reports
- MeSH: Diabetes Mellitus, Type 1; complications; surgery; Duodenum; transplantation; Female; Follow-Up Studies; Graft Rejection; prevention & control; Humans; Immunosuppressive Agents; therapeutic use; Liver Cirrhosis; complications; surgery; Liver Neoplasms; complications; surgery; Liver Transplantation; Male; Middle Aged; Pancreas Transplantation; Transplantation, Homologous
- From: Chinese Journal of Surgery 2006;44(3):157-160
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the effect of treatment on end-stage liver disease and type-I diabetes mellitus with simultaneous liver-pancreas-duodenum transplantation.
METHODIn September 2003, one patient with chronic hepatitis B, liver cirrhosis, hepatic cellular cancer, and insulin-dependent diabetes received simultaneous orthotopic liver and heterotopic pancreas-duodenum transplantation. Liver and pancreas graft function was monitored after transplantation.
RESULTSThe function of pancreas allograft was recovered immediately and the patient became insulin-independence postoperatively. The liver allograft was experienced an acute rejection episode and reversed by intravenous bolus methylprednisolone. The recipient was currently liver disease-free and insulin-free more than 21 months.
CONCLUSIONSThe simultaneous liver-pancreas-duodenum transplantation is an effective method in the treatment of end-stage liver disease and type-I diabetes mellitus.
