The rule of proliferation after sciatic injury of rats: immunohistological observation.
- Author:
Fu-qiang ZHAO
1
;
Bao-guo JIANG
;
Pei-xun ZHANG
;
Hong-bo ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Anastomosis, Surgical; Animals; Cell Proliferation; Immunohistochemistry; Male; Rats; Rats, Sprague-Dawley; Schwann Cells; cytology; Sciatic Nerve; injuries; pathology; surgery; Time Factors
- From: Chinese Journal of Surgery 2006;44(4):268-270
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo describe the rule of the schwann cell proliferation after peripheral nerve injury in detail and to discover the effect of neuroanastomosis.
METHODSThe model of rat sciatic injury was made, with neuroanastomosis on the left side and right side untreated. Then draw the materials 24, 48 h, 4, 7, 14, 21 d after surgery. And immunohistological stain counted the schwann cell per view with Qwin software of Leica Ltd.
RESULTSThe number of schwann cell increased obviously 4 d after surgery and reached the peak in 7 d. Then it fell down and the neuroanastomosis group changed slower and fibroblast hyperplasia in the untreated.
CONCLUSIONSThe axon support is essential for the schwann cell. The precise rule is help for study on neurotrophic factor.
