Variation of T lympho counts in peripheral blood of idiopathic aplastic anemia patients and the treatment with cyclosporine.
- Author:
Oanh Hoang Le
- Publication Type:Journal Article
- Keywords:
aplastic anemia
- MeSH:
Anemia, Aplastic;
therapy;
blood;
therapeutics;
cyclosporine
- From:Journal of Medical and Pharmaceutical Information
1999;(12):24-28
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
From 11/1995 to 4/1999 we treated by prednisone for 15 patients and CsA for 16 ones with idiopathic aplastic anemia. Results:- Prednison did not change significantly TCD3, TCD4 and TCD8 colony count comparing with pre-treatment (P>0.05).- CsA decreased clearly TCD3 colony count after 1st, 6th month (P<0,05). However, TCD4 colony count decreased not significantly (P>0.05). Conclusions: CsA has more suppressive effect on T-cell colonies, mainly TCDz3 and TCD8 than Prednisone and therefore it may be chosen to treat patients with idiopathic aplastic anemia without indication for bone marrow transplantation.
