The comparison of the WHO standard rabies immunoglobulin and the national standard Human rabies immunogiobulin used in the rapid fluorescent focus inhibition test (RFFIT)
10.3760/cma.j.issn.1003-9279.2010.02.005
- VernacularTitle:狂犬病抗血清WHO标准品和国家标准品用于RFFIT方法的比较
- Author:
Peng-Cheng YU
1
;
Xin-Xin SHEN
;
Xin-Jun LV
;
Hu SHAN
;
Qing TANG
Author Information
1. 中国疾病预防控制中心
- Keywords:
Reference standards;
Rapid fluorescent focus inhibition test;
Neuralization tests
- From:
Chinese Journal of Experimental and Clinical Virology
2010;24(2):91-93
- CountryChina
- Language:Chinese
-
Abstract:
Objective Compare the difference of the results referred to the WHO standard rabies immunoglobulin and the national standard human rabies immunoglobulin used in the rapid fluorescent focus inhibition test (RFFIT).Methods Setting the WHO standard immunoglobulin and the national standard immunoglobulin in the same system and testing 12 human serum at the same time.Compare the fluorescence percentage of the two different standard immunoglobulin;compare the 12 serum results calculated from the two different standard immunoglobulin used the calculation formula of neutralization antibody titer.Results The Results display that the 50% percent of the two standard immunoglobulin are all between the fifth and the sixth well,but the percentage of the national standard immunoglobulin is lower than the WHO one.The same testserum result calculated from the WHO standard immunoglobulin is little higher than the national one.Conclusion There is difference in the WHO standard immunoglobulin and the national one,but there is no influence in the results.
