Study on the correlation of Xinjiang endometrial tumor and vascular endothelial growth factor
10.3760/cma.j.issn.1003-9279.2010.02.007
- VernacularTitle:血浆VEGF水平在维吾尔族妇女子宫内膜癌中表达及意义
- Author:
Xin-Ling WANG
1
;
Ze-Min PAN
;
A Na Gu Li.A-Ba Bai Ke Li
;
Ming-Yue ZHU
Author Information
1. 新疆医科大学附属肿瘤医院
- Keywords:
Endothelium,vascular;
Receptors,growth factor;
Endometrial neoplasms
- From:
Chinese Journal of Experimental and Clinical Virology
2010;24(2):98-100
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationships of serum vascular endothelial growth factor (VEGF) and endometrial cancer of Uighur Women in Xinjiang.Methods The serum of 50 endometrial cancer patient's and 70 healthy women's were collected.VEGF expressions were tested by ELISA method and the correlations of endometrial cancer with VEGF were analysed.The variety of serum VEGF in different clinical stages of endometriat cancer was analyzed.Results Serum VEGF expressions on endometrial cancer were significantly higher than normal ones (P＜0.01);The serum VEGF level in late stage was significantly higher than early stage (P＜0.01).The serum VEGF level significantly increased from well differentiated to the poorly differentiated cases (P＜0.05).Conclusion high level expressions of VEGF are related to the endometrial cancer.Uighur Women in Xinjiang,particularly high expressed in advanced and poorly differentiated endometrial cancer.
