Analyze the antibody level of enterovirus 71 about children cases of hand-foot-mouse disease outbreak.
- Author:
Kun JU
1
;
Lin-En JIANG
;
Wei LI
;
Hui-Qing REN
;
Xu-Hua JING
;
Bao-Hui JIN
Author Information
- Publication Type:Journal Article
- MeSH: Child, Preschool; Enterovirus; immunology; pathogenicity; Enzyme-Linked Immunosorbent Assay; Female; Hand, Foot and Mouth Disease; virology; Humans; Immunoglobulin G; immunology; Immunoglobulin M; immunology; Infant; Male
- From: Chinese Journal of Experimental and Clinical Virology 2010;24(2):139-141
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo analyze the Enterovirus 71 infectious status about probably cases of hand-foot-mouse disease (HFMD).
METHODSCollect the blood samples of HFDM children probably cases and test the IgG, IgM antibody by ELISA, analyzed the age and gender distribution.
RESULTSWe collected 159 blood samples of children probably cases who are 1 to 5 years old. The average EV71 IgG positive rate is 63.5%, which of IgM is 12.0%. The positive rate of EV71 IgG is decrease by aged. Male's EV71 IgM positive rate is higher than female's significantly.
CONCLUSIONThe pathogen of this case of HFMD outbreak is EV71. Male's EV7l infectious and incidence are higher than female's. The result of this investigation could provide information to HFMD disease control.
