Evaluation on clinical value of serum CA-125 level in hepatitis cirrhosis.
- Author:
Jun XU
1
;
Jia LIU
;
Jing-xia GUO
;
Hong-bin MA
;
Jing ZHAO
;
Ai-xia LIU
;
Wei-ning XU
;
Bo-an LI
;
Yuan-li MAO
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Aged, 80 and over; Ascites; pathology; CA-125 Antigen; blood; Female; Humans; Liver; pathology; Liver Cirrhosis; blood; pathology; Male; Middle Aged; Young Adult
- From: Chinese Journal of Experimental and Clinical Virology 2010;24(5):334-336
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo determine the association between elevated levels of serum cancer antigen (CA) 125 and hepatitis cirrhosis in different stage, and also to explore the clinical application value of serum CA-125.
METHODSDuring June to December in 2008, 200 cases with hepatitis cirrhosis were random selected in our hospital. CA-125 levels were measured by electrochemiluminescence immunization assay in sera collected from these cases which were termed with Child-Paugh classification and analyzed by SAS.
RESULTSSerum CA-125 levels were correlated closely with ascites, primary peritonitis and liver function Child-Paugh classification, but no associated with primary carcinoma of liver and other liver function index,such as ALT, AST, ALB, TBIL and PT.
CONCLUSIONThe levels of serum CA-125 in hepatitis cirrhosis patients were osculating correlating with lesion of liver and ascite degree, could serve as a sensitive and conventional laboratory index for liver lesion degree and monitoring ascite generation. It was necessary to further study on the association with serum CA-125 level with primary hepatic carcinoma.
