Evaluation on clinical value of serum CA-125 level in hepatitis cirrhosis
10.3760/cma.j.issn.1003-9279.2010.05.005
- VernacularTitle:乙型肝炎肝硬化患者血清CA-125表达水平临床研究
- Author:
Jun XU
1
;
Jia LIU
;
Jing-Xia GUO
;
Hong-Bin MA
;
Jing ZHAO
;
Ai-Xia LIU
;
Wei-Ning XU
;
Bo-An LI
;
Yuan-Li MAO
Author Information
1. 解放军第302医院
- Keywords:
Liver cirrhosis;
Ascites;
Glycoproteins;
Child-Pugh classification;
Peritonitis
- From:
Chinese Journal of Experimental and Clinical Virology
2010;24(5):334-336
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the association between elevated levels of serum cancer antigen (CA) 125 and hepatitis cirrhosis in different stage, and also to explore the clinical application value of serum CA-125. Methods During June to December in 2008, 200 cases with hepatitis cirrhosis were random selected in our hospital. CA-125 levels were measured by electrochemiluminescence immunization assay in sera collected from these cases which were termed with Child-Paugh classification and analyzed by SAS. Results Serum CA-125 levels were correlated closely with ascites, primary peritonitis and liver function Child-Paugh classification, but no associated with primary carcinoma of liver and other liver function index,such as ALT, AST, ALB, TBIL and PT. Conclusion The levels of serum CA-125 in hepatitis cirrhosis patients were osculating correlating with lesion of liver and ascite degree, could serve as a sensitive and conventional laboratory index for liver lesion degree and monitoring ascite generation. It was necessary to further study on the association with serum CA-125 level with primary hepatic carcinoma.
