Analysis of neutralized antibody level of the poliomyelitis in healthy population in Fujian province.
- Author:
Ai-hua HE
1
;
Hong WANG
;
Xiu-hui YANG
;
Jiang-yang XU
;
Hong-rong ZHANG
;
Li-fang HUANG
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Antibodies, Neutralizing; blood; immunology; Antibodies, Viral; blood; immunology; Child; Child, Preschool; China; Female; Health Status; Humans; Infant; Male; Middle Aged; Poliomyelitis; immunology; prevention & control; virology; Poliovirus Vaccine, Oral; administration & dosage; immunology; Population Surveillance; Vaccination; Young Adult
- From: Chinese Journal of Experimental and Clinical Virology 2010;24(5):352-354
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo understand the neutralized antibody level of the poliomyelitis among healthy people and provide scientific evidence for the immunization strategy since routine and intensified immunization with oral polio vaccine (OPV) in Fujian province.
METHODSThe poliomyelitis antibody level of healthy people were detected by neutralization test of the micro cells.
RESULTSThe neutralizing antibody positive rates were 99.0%, 99.3%, 97.5% and GMTs were 1:79.1, 1:31.2, 1:24.7 for polio I, II, III respectively in 400 serum specimens from 1-59 years old. GMTs present a trend of decreasing as age's increasing.
CONCLUSIONA protective barrier had been built against poliomyelitis in healthy people in Fujian province through routine and intensified immunization with OPV.
