Pathological description and immunohistochemical demonstration of ovine abortion associated with Toxoplasma gondii in Iran.
- Author:
Maryam RASSOULI
1
;
Golam Reza RAZMI
;
Ahmad Reza MOVASSAGHI
;
Mohammad Reza BASSAMI
;
Mehrdad SAMI
Author Information
1. Department of Pathobiology, School of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad 9177948974, Iran. Grrazmii@yahoo.com
- Publication Type:Original Article
- Keywords:
histopathology;
immunohistochemistry;
Iran;
ovine abortion;
Toxoplasma gondii
- MeSH:
Brain;
Fetus;
Gestational Age;
Heart;
Immunohistochemistry;
Iran;
Kidney;
Liver;
Logic;
Lung;
Parasites;
Toxoplasma
- From:Korean Journal of Veterinary Research
2013;53(1):1-5
- CountryRepublic of Korea
- Language:English
-
Abstract:
The obligatory intracellular protozoan parasite Toxoplasma gondii is a major world wide cause of infectious ovine abortion. In some different diagnostic techniques that are being used to detect this pathogen in ovine fetuses, immunohistochemistry (IHC) is a very sensitive and expensive one. Histopathology is not truly a specific and sensitive test for Toxoplasma infection but it can be helpful to choose some suspected tissues for IHC. In this study 9.5% of 200 samples (aborted ovine fetuses internal organs such as brain, liver, heart, lung, kidney, spleen) (4.6~14.4% with 95% CI) were positive in IHC with a very good logical agreement among different diagnostic techniques (kappa = 0.73, 0.8) and with no significant difference among different fetal age groups (p > 0.05).