Production of serum against neurotoxin alpha from NAJA KAOUTHIA.
- Author:
Thu Thi Nguyet Nguyen
- Publication Type:Journal Article
- Keywords:
antitoxin
- MeSH:
Neurotoxins;
serum
- From:Journal of Preventive Medicine
2002;12(1):17-23
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Lethal component of the Naja kaouthia venom had been purified and used as antigen for producing antiserum according to an immunization protocol aiming to be efficient in the production of high affinity antibodies. A strong response was observed on all six immunized horses and tolerance to the antigen did not occur. All antitoxin sera obtained protected against lethality due to the entire venom. The potential production of these six horses is estimated to 4,300 doses/year compared to the estimated national need of 4,800 doses/year for a population of 80 millions.
