Comparison of clinical characteristics between patients with non-allergic and allergic rhinitis
10.3760/cma.j.issn.1673-0860.2012.07.008
- VernacularTitle:非变应性鼻炎与变应性鼻炎患者临床特征分析
- Author:
Lu-Ping ZHU
1
;
Qi-Lei TAO
;
Mei-Ping LU
;
Yun-Li WANG
;
Ruo-Xi CHEN
;
Yi LU
;
Yan SHEN
;
Lei CHENG
Author Information
1. 南京医科大学附属第一医院
- Keywords:
Rhinitis,allergic,perennial;
Rhinitis,allergic,seasonal;
Rhinitis,vasomotor;
Disease attributes;
Diagnosis,differential
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2012;47(7):559-564
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze and compare the differences of clinical characteristics and comorbidities between patients with non-allergic rhinitis (NAR) and allergic rhinitis (AR).Methods A total of 556 out-patients were enrolled from January 2010 to June 2011.The chief complaints of the patients included at least two of the following nasal symptoms:nasal congestion,rhinorrhea,sneezing,and nasal itching.Based on the results of the disease history,physical examination and allergen skin prick test,the patients were classified into NAR group (n =206) and AR group (n =350).Detailed information including general data,nasal symptoms and signs,accompanied symptoms and comorbidities were obtained by questionnaires.A scoring was adopted to estimate the severity of disease.SPSS 13.0 software was applied for statistical analysis.Results The mean age of NAR patients ( 31.8 ± 16.7 ) was older than that of AR patients (26.3 ± 14.8),and the difference was significant (t =4.01,P =0.0001 ).While there was no significant difference on gender distribution between two groups (x2 =0.12,P =0.73 ).The percentage of nasal congestion was not significantly different between NAR and AR patients (89.8％ and 92.0％,respectively; x2 =0.26,P =0.611 ).However,the symptoms of rhinorrhea,sneezing,nasal itching,eyes itching,lachrymation,wheeze and cough were more popular in AR patients than those in NAR patients (all P ＜ 0.05 ).Moreover,above symptoms ( except cough) were more serious in AR patients,and the symptom scores were significantly higher than those in NAR patients ( all P ＜ 0.05 ).Most of patients with NAR (67.0％) and AR ( 62.9％ ) were moderate-severe persistent ( x2 =1.25,P =0.264 ).Accompanied asthma were more common in patients with AR ( 12.6％ ) compared with NAR (2.4％ ),while hypertension were more common in patients with NAR (7.3％) compared with AR ( 1.7％ ),and the differences were significant ( both P ＜ 0.05 ).Conclusion NAR and AR are two different disease entities,which have different clinical characteristics,as well as different comorbidities.Further clinical study should be done on the rhinitis phenotypes.
