Chemical constituents from roots of Platycodon grandiflorum.
- Author:
Ling-Jun LI
1
;
Zhen-Hua LIU
;
Yun CHEN
;
Jing-Kui TIAN
Author Information
- Publication Type:Journal Article
- MeSH: Flavones; chemistry; isolation & purification; Lactones; chemistry; isolation & purification; Oleanolic Acid; analogs & derivatives; chemistry; isolation & purification; Plant Extracts; chemistry; isolation & purification; Plant Roots; chemistry; Plants, Medicinal; chemistry; Platycodon; chemistry; Saponins; chemistry; isolation & purification
- From: China Journal of Chinese Materia Medica 2006;31(18):1506-1509
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the chemical constituents from roots of Platycodon grandiflorum.
METHODColumn chromatography (silica gel, macroporous resin, sephadex LH - 20 and the preparative RP - HPLC were used to isolate the constituents. Their structures were elucidated by physical and spectral data.
RESULTEight compounds were isolated and identified as tangeritin (1), 3-O-beta-D-glucopyranosylplatycodigenin methyl ester (2), 3-O-beta-D-glucopyranosylplaticogenic acid A lactone (3), 3-O-beta-D-glucopyranosylplatycodigenin (4), deapio-platyconic acid A lactone (5), deapio-platycodin-D (6), platycoside-G1 (7) and platycoside-E (8).
CONCLUSIONCompounds 1,3 and 5 were isolated from this plant for the first time.