Studies on HPLC fingerprint of cortex moutan.
- Author:
Shun-Jun XU
1
;
Peng LI
;
Liu YANG
;
Mian ZHANG
;
Zheng-Tao WANG
Author Information
- Publication Type:Journal Article
- MeSH: Acetophenones; analysis; Bridged Bicyclo Compounds, Heterocyclic; analysis; Chromatography, High Pressure Liquid; methods; Drugs, Chinese Herbal; analysis; chemistry; classification; Gallic Acid; analogs & derivatives; analysis; Glucosides; analysis; Hydrolyzable Tannins; analysis; Monoterpenes; analysis; Paeonia; chemistry; classification; Plant Bark; chemistry; Plants, Medicinal; chemistry; Quality Control
- From: China Journal of Chinese Materia Medica 2006;31(20):1677-1680
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo establish a HPLC fingerprint for quality evaluation of Cortex Moutan.
METHODThe HPLC chromatographic fingerprinting of 30 lots of Cortex Moutan was established and major peaks were identified by LC-MS and MS-MS.
RESULTThe HPLC fingerprint of Cortex Moutan was established, showing 15 characteristic peaks. The areas of these peaks were found to complied with the following rule: paeonol > 1, 2, 3, 4, 6-penta-O-galloyl-glucos > methyl gallate > galloylpaeoniflorin > gallic acid > oxypaeoniflorin > other compounds.
CONCLUSIONThe chromatographic fingerprinting of Cortex Moutan with high specificity can be used to control its quality and monitor lot to lot consistency.
