Study on anti-tumor effect of medicinal fungi Phellinus igniarius extracts.
- Author:
Quan YANG
1
;
Xu-Guang HU
;
Qi WAN
;
Wen-Quan WANG
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Antineoplastic Agents; isolation & purification; pharmacology; Mice; Neoplasm Transplantation; Polyporaceae; chemistry; Polysaccharides; isolation & purification; pharmacology; Sarcoma 180; pathology; Spleen; pathology; Thymus Gland; pathology
- From: China Journal of Chinese Materia Medica 2006;31(20):1713-1715
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the inhibiting effect of medicinal fungi Phellinus igniarius extracts on S180 tumor and the immunoregulation effect on the S180-induced tumor mice.
METHODS180 mice were orally given 100, 200, 400 mg x kg(-1) dosage of P. igniarius extracts, then the inhibition grow effect, spleen index, and thyme index were measured.
RESULTMedicinal fungi P. igniarius extracts can increase the spleen index and thyme index and the inhibiting tumor rate was 31.88%, 46.25%, 53.13%, respectively. Also, medicinal fungi P. igniarius extracts can prolong life in mice.
CONCLUSIONThe medicinal fungi P. igniarius extracts show obviously anti-tumor effect and immunoregulation effect.
