Effects of annao tablet on S100B and NPY of cortex in chronic epilepsy rats.
- Author:
Ruo-Ming FANG
1
;
Geng-Li FANG
;
Yong-Qi FANG
Author Information
- Publication Type:Journal Article
- MeSH: Acorus; chemistry; Animals; Anisoles; administration & dosage; isolation & purification; pharmacology; Anticonvulsants; administration & dosage; isolation & purification; pharmacology; Cerebral Cortex; metabolism; Drug Carriers; Epilepsy; metabolism; physiopathology; Female; Male; Neuropeptide Y; metabolism; Plants, Medicinal; chemistry; Rats; Rats, Sprague-Dawley; S100 Proteins; metabolism; Tablets; beta-Cyclodextrins
- From: China Journal of Chinese Materia Medica 2006;31(20):1719-1721
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the effects of Annao tablet (main component is beta-asarone) on S100B and NPY of cortex in chronic epilepsy rats.
METHODThe remedy was administered orally. The effects were observed in convulsion model induced by PG, then S100B protein and NPY of cortex were determined.
RESULTAnnao tablet could depress the epileptic degree, postpone spasm latent period and reduce the wet dog sample (WDS) times. The remedy could decline S100B and NPY of cortex in chronic epilepsy rats.
CONCLUSIONAnnao tablet has obvious antiepileptic effects and can reduce the nerve cell damage induced by epilepsy.
