Study on fast screening antifungus activity of endophytes from Pseudolarix kaempferi.
- Author:
Jia HE
1
;
Jun CHEN
;
Qi-Mei ZHAO
;
Hong-Bing QI
Author Information
- Publication Type:Journal Article
- MeSH: Antifungal Agents; isolation & purification; pharmacology; Candida albicans; drug effects; Cryptococcus; drug effects; Fungi; chemistry; classification; isolation & purification; Mitosporic Fungi; drug effects; Pinaceae; microbiology; Plants, Medicinal; microbiology; Symbiosis; Trichophyton; drug effects
- From: China Journal of Chinese Materia Medica 2006;31(21):1759-1763
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo screen antifungal activity of endophytes from Pseudolarix kaempferi.
METHODEndophytes from P. kaempferi were separated. By means of microdilution method, antifungal active endophytes were fast screened by Pyricularia oryzae P-2b model, and activity of endophytes against pathogenic fungus was studied.
RESULT44.8% of endophytes showed activity against P. oryzae P-2b in Pseudolarix kaempferi. Among them JJ314, JJ323 introduced formation of characteristic beads and swellings on the growing hyphae, JJ324 inhibited the conidia germination. They all showed activity against Trichophyton rubrum, Cryptococcus neoformans and Candida albicans.
CONCLUSIONEndophytes from P. kaempferi are a potential resource for the development of antifungal agent.