Application of adipose-derived mesenchymal stem cells in craniomaxillofacial restoration and reconstruction.
- Author:
Mingyang SHU
1
;
Lei LIU
2
Author Information
1. State Key Laboratory of Oral Diseases, Dept. of Traumatic and Plastic Surgery, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
2. State Key Laboratory of Oral Diseases, Dept. of Traumatic and Plastic Surg
- Publication Type:Journal Article
- MeSH:
Adipose Tissue;
Humans;
Mesenchymal Stromal Cells;
Reconstructive Surgical Procedures;
Tissue Engineering
- From:
West China Journal of Stomatology
2013;31(6):644-647
- CountryChina
- Language:Chinese
-
Abstract:
Craniomaxillofacial hard and soft tissue defects are clinically common and frequently encountered diseases that seriously affect the appearance and function of patients. Restoration and reconstruction of craniomaxillofacial hard and soft tissues are comprehensive clinical problems that require a multi-disciplinary approach and are faced with many unresolved issues. Development of tissue engineering has introduced new concepts to craniomaxillofacial restoration and reconstruction. Tissue engineering primarily aims to determine suitable seed cells. Recently, adipose-derived mesenchymal stem cells (AdSCs) were found to be relatively ideal seed cells because they are easy to obtain from numerous sources and have multiple potencies under certain inducing circumstances and high augmenting ability. This review provides an overview of the application of AdSCs in craniomaxillofacial restoration and reconstruction.
