Correlation between lung volume and the severity of obstructive sleep apnea hypopnea syndrome in obese patients.
- Author:
Rong-gang YANG
1
;
Jing-ying YE
;
Yu-huan ZHANG
;
Yang WANG
;
Xin CAO
;
Jun-bo ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Body Mass Index; Humans; Lung Volume Measurements; Male; Obesity; epidemiology; Oximetry; Polysomnography; Sleep Apnea, Obstructive; epidemiology; pathology
- From: Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2013;48(4):295-299
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo examine the relationship between the severity of obstructive sleep apnea hypopnea syndrome (OSAHS), lung volume and obesity.
METHODSThe study included 60 adult male obese patients with OSAHS determined by overnight polysomnogram (PSG) using American Academy of Sleep Medicine-defined criteria. Lung volume measurements were made in maximum vital capacity (VCmax), forced vital capacity (FVC), maximum voluntary ventilation (MVV), functional residual capacity (FRC) and total lung capacity (TLC).
RESULTSThe aponea hypopnea index (AHI) were negatively correlated with FVC, MVV, VCmax (r were -0.533, -0.276 and -0.575, P < 0.01 or P < 0.05). But the lowest arterial oxygen saturation (LSaO2) and the mean arterial oxygen saturation (MSaO2) were positively correlated with FVC, MVV and VCmax (r were 0.299, 0.435, 0.412, and 0.344, 0.474, 0.457, P < 0.01 or P < 0.05). The body mass index (BMI) were positively correlated with AHI (r = 0.728, r(2) = 0.530, P < 0.01). The FVC, MVV, VCmax, LSaO2 and MSaO2 varied inversely with BMI. FRC and TLC had no relation with AHI, LSaO2, MSaO2 and BMI.
CONCLUSIONSThere are significant correlations among obesity, dynamic lung volume and OSAHS severity. This result suggests that changes in dynamic lung volume may play an important role in the pathogenesis of OSAHS in obese patients.
