Micro-focus X-ray for cochlear implantation research on small animals.
- Author:
Wei LU
1
;
Jin XU
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Cats; Cineradiography; methods; Cochlea; diagnostic imaging; Cochlear Implantation; Cochlear Implants; Guinea Pigs; Rats; X-Rays
- From: Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2006;41(9):702-704
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo develop an imaging system suitable for cochlear implant research on small laboratory animals.
METHODSA novel micro-focus X-ray imaging system was developed. The key features of the system were the use of a micro-focus X-ray source (less than 10 micrometers) and an appropriate choice of source-object and object-image distance. The new X-ray modality was evaluated on heads of cats, guinea pigs and rats.
RESULTSIt proved to be an useful tool to provide excellent image of small animal cochlea, allowing a clear electrode position to be established, and also helped greatly in detecting the breakage of electrode array.
CONCLUSIONSExperimental studies performed in cats, guinea pigs and rats confirmed that micro-focus radiography was an important tool for cochlear implant research in laboratory
