Screening antifungal drugs and essential oil
- Author:
Nga Dinh Nguyen
- Publication Type:Journal Article
- Keywords:
antifungal drug
- MeSH:
Antifungal Agents;
Oils, Volatile;
Medicine, Traditional;
Pharmaceutical Preparations;
therapeutics
- From:Pharmaceutical Journal
1999;282(10):12-14
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The antifungal activity of 10 vegetable essential oils and 10 traditional medicinal herbs was examined by measuring the minimum growth inhibitory concentration against three groups of fungi: yeast (Cadida albicans), mould (Aspergillus flavus, Aspergillus fumigatus, Aspergillus niger), and dermatophytes (Microsporum gypseum, trichophyton mentagrophytes). The essential oil of Cinnamon and the Alpinia galanga extract showed the strongest effect against all three groups of fungi. The combination effects of Cinnamon essential oil and 3 extracts of traditional medical herbs were determined by the agar dilution method against Candida albicans. The combination of Cinnamon essential oil and A. galanga extract at proportions (1:1) or (3:7) were synergist and the combinations of Cinnamon essential oil and Curcuma longa extract (1:1) or Chrysantherum indicum extract (1:1) were additive.
