Gender Differences in Diagnostic Values of Visceral Fat Area and Waist Circumference for Predicting Metabolic Syndrome in Koreans.
10.3346/jkms.2011.26.7.906
- Author:
Hong Il KIM
1
;
Jin Taek KIM
;
Sung Hoon YU
;
Soo Heon KWAK
;
Hak Chul JANG
;
Kyong Soo PARK
;
Seong Yeon KIM
;
Hong Kyu LEE
;
Young Min CHO
Author Information
1. Divisions of Endocrinology and Metabolism, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. ymchomd@snu.ac.kr
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Metabolic Syndrome;
Visceral Fat Area;
Waist Circumference;
ROC Curve Analysis
- MeSH:
Adult;
Aged;
Aged, 80 and over;
Female;
Humans;
Insulin Resistance;
Intra-Abdominal Fat/*radiography;
Male;
Metabolic Syndrome X/*diagnosis/epidemiology;
Middle Aged;
Postmenopause;
*Predictive Value of Tests;
ROC Curve;
Republic of Korea/epidemiology;
Risk Factors;
Sex Factors;
*Waist Circumference
- From:Journal of Korean Medical Science
2011;26(7):906-913
- CountryRepublic of Korea
- Language:English
-
Abstract:
Abdominal fat accumulation is known to be strongly implicated in development of metabolic syndrome (MetS). We examined diagnostic values of obesity-related parameters in 95 men and 185 women, and we determined optimal cutoff values of visceral fat area (VFA) and waist circumference (WC) for predicting the presence of multiple non-adipose components of MetS. Receiver operating characteristic (ROC) curve analysis revealed that VFA was the best indicator of MetS. WC and VFA exhibited similar diagnostic values for men and postmenopausal women, whereas WC was inferior to VFA for premenopausal women (area under ROC curve of VFA and WC was 0.76 and 0.52, respectively; P < 0.001). Optimal cutoff points of VFA and WC for predicting MetS were 136 cm2 and 89 cm in men and 95 cm2 and 82 cm in women, respectively. Subjects with VFA and WC above these cutoff values exhibited increased insulin resistance and increased carotid intima-media thickness. In conclusion, WC has a diagnostic value similar to VFA for predicting MetS in men and postmenopausal women, but not in premenopausal women. Further studies are necessary to develop a simple clinical parameter that reflects visceral fat in premenopausal women.
