Compatability chemistry of acid-alkaline pair medicine of Ephedra sinica and Glycyrrhiza uralencis in Maxing Shigan decoction.
- Author:
Xiangping PEI
1
;
Miaorong PEI
;
Xiujun DUAN
Author Information
- Publication Type:Journal Article
- MeSH: Chemistry, Pharmaceutical; Drugs, Chinese Herbal; chemistry; Ephedra sinica; chemistry; Ephedrine; chemistry; Glycyrrhiza; chemistry; Glycyrrhizic Acid; chemistry
- From: China Journal of Chinese Materia Medica 2009;34(19):2466-2468
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the change regularity of ephedrine and glyrihhzine acid in Ephedra sinila and Glycyrrhiza uralencis pair medicines and in Maxing Shigan decoction.
METHODThe contents of ephedrine and glycyrrhizic acid were determined by HPLC in samples of E. sinica extracts, G. uralencis extracts, pair medicines extracts of Maxing Shigao decoction sinica and G. uralencis, and extracts of E. sinica.
RESULTThere were no significant difference in ephedrine contents amoung different samples; the contents of glycyrrhizic acid were lower in decoctions of Maxing Shigan decoction than in G. uralencis decoction and pair medicines extracts.
CONCLUSIONMacromolecular complex was NOT formed by ephedrine and Glycyrrhizic acid in decoctions containing pair medicines of E. sinica and G. uralencis.