Bioactive constituents from whole herbs of Vernonia cinerea (II).
- Author:
Huaxu ZHU
1
;
Yuping TANG
;
Zhida MIN
;
Zhunan GONG
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Drugs, Chinese Herbal; chemistry; pharmacology; PC12 Cells; Rats; Vernonia; chemistry
- From: China Journal of Chinese Materia Medica 2009;34(21):2765-2767
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the constituents of the whole herbs of Vernonia cinerea by bio-activity guided isolation with PC-12 model.
METHODThe constituents were separated by column chromatography and the structures were elucidated by spectroscopic methods.
RESULTTen compounds were identified to be (-)-clovane-2,9-diol (1), caryolane-1,9beta-diol (2), apigenin (3), chrysoeriol (4), luteolin (5), thermopsoside (6), luteolin-7-O-beta-D-glucoside (7), quercetin(8), apigenin-4'-O-beta-D-glucoside (9), hyperin (10), beta-amyrin aceate (11), lupeol acetate (12).
CONCLUSIONCompounds 1, 2, 6 and 10 were isolated from this genus for the first time.
