Assay of evodin, evodiamine and rutaecarpine in Fructus Evodiae by QAMS.
- Author:
Yafang SONG
1
;
Zhimin WANG
;
Jingjing ZHU
;
Lihua YAN
;
Qiwei ZHANG
;
Muxin GONG
;
Huimin GAO
;
Weihong FENG
;
Weihao WANG
Author Information
- Publication Type:Journal Article
- MeSH: Chromatography, High Pressure Liquid; methods; Drugs, Chinese Herbal; analysis; Evodia; chemistry; Furans; analysis; Heterocyclic Compounds, 4 or More Rings; analysis; Indole Alkaloids; analysis; Plant Extracts; analysis; Quinazolines; analysis
- From: China Journal of Chinese Materia Medica 2009;34(21):2781-2785
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo develop a Quantitative Assay of Multi-components by Single - marker (QAMS) for simultaneous determination of three components in Fructus Evodiae, and examine the feasibility of using the relative correction factors between the different types of compounds.
METHODRutaecarpine was selected as the internal reference substance; the relative correction factors of evodin and evodiamine were calculated. The contents of three components in 11 batches of samples were determined by both external standard method and QAMS. The validity of the QAMS method was evaluated by comparison of their quantitative results.
RESULTNo obvious differences (RSD < 5%) were found in the quantitative results of evodin and evodiamine in 11 batches of Fructus Evodiae determined by the two methods.
CONCLUSIONIt is feasible and suitable to determine evodin and evodiamine in Fructus Evodiae by QAMS, and this method can be used for a certain different types of compounds.
