Research development of HIV drug resistance.
- Author:
Wen ZOU
1
;
Ying LIU
;
Jian WANG
;
Guo-Jian GAO
;
Ji-Peng DONG
;
Qing-Fei XIAN
Author Information
1. AIDS Research Center, China Academy of Chinese Medical Sciences, Beijing 100700, China. veven@yeah.net
- Publication Type:Journal Article
- MeSH:
Anti-HIV Agents;
pharmacology;
Drug Discovery;
Drug Resistance, Viral;
HIV;
drug effects;
enzymology;
Humans;
Internationality
- From:
China Journal of Chinese Materia Medica
2013;38(15):2542-2544
- CountryChina
- Language:Chinese
-
Abstract:
Highly active antiretroviral combination therapy significantly reduced the mortality, but in the high-speed copying, high genetic variation and drug selection pressure under the effect of the increasingly serious problem of drug resistance greatly weakened the role of HAART inhibit viral replication and reduce antiviral treatment. This paper reports the latest trends in HIV drug-resistance in order to develop anti-HIV drugs in clinical programs, research and development of new guidance anti-HIV-1 strategy to bring guidance.
