Chemical constituents of Paederia pertomentosa.
- Author:
Hai-Qing HU
1
;
He-Dong HAN
;
Yan LIN
;
Lian-Hong CHEN
;
Xiao-Ling WANG
Author Information
1. Ethnic Pharmaceutical Institute, Southwest University for Nationalities, Chengdu 610041, China. 1903388407@qq.com
- Publication Type:Journal Article
- MeSH:
Drugs, Chinese Herbal;
analysis;
isolation & purification;
Rubiaceae;
chemistry
- From:
China Journal of Chinese Materia Medica
2013;38(16):2657-2660
- CountryChina
- Language:Chinese
-
Abstract:
Five constituents were extracted from the aerial part of Paederia pertomentosa and isolated by column chromatography. Their structures were elucidated by physicochemical properties and spectroscopic data analysis. The isolated compounds were identified as 1,2-dimethoxy-3,4-dihydroxyanthraquinone named as paederone (1), paederoside (2), deacetyl asperulosidic acid methyl ester (3), paederosidic acid (4) and methylpaederosidate (5). Compound 1 is a new compound which exhibits a significant inhibitory effect on Escherichia coli and Staphylococcus aureus. Compounds 2-5 were isolated from this plant for the first time.
