Chemical constituents of chloroform fraction from leaves of Chimonanthus salicifolius.
- Author:
Yao ZHANG
1
;
Jin-Wei HUA
;
Xiu-Yan WANG
;
Wen-Liang CHENG
;
Hou-Xing LEI
;
Ke-Jun CHENG
;
Pei-Zhong YU
Author Information
1. School of Pharmacy, Fudan Univerisity, Shanghai 201203, China.
- Publication Type:Journal Article
- MeSH:
Antineoplastic Agents;
analysis;
isolation & purification;
Calycanthaceae;
chemistry;
Chloroform;
chemistry;
Drugs, Chinese Herbal;
analysis;
isolation & purification;
Plant Leaves;
chemistry
- From:
China Journal of Chinese Materia Medica
2013;38(16):2661-2664
- CountryChina
- Language:Chinese
-
Abstract:
To explore anti-tumor active components of Chimonanthus salicifolius, the phytochemistry of the chloroform fraction from leaves extract was investigated by repeated silica gel column chromatography. Twelve compounds were isolated and their structures were identified by physicochemical properties and spectroscopic data analysis as 9-epi-blumenol C(1), blumenol C(2), (+)-dehydrovomifoliol (3), (+)-vomifoliol (4), robinlin (5), (-)-loliolide (6), isofraxidin (7), scopoletin (8), 6,7-dimethoxycoumarin (9), 6, 7, 8-trimethoxycoumarin (10), beta-sitostenone (11), and beta-stigmasterol(12). Compounds 1-6 belonging to nor-sesquiterpenoids were isolated from the family Calycanthaceae for the first time. Compound 1 was a new natural product. Compounds 7, 11 and 12 were obtained from this plant for the first time.
