The effect of postoperative transcatheter hepatic arterial chemoembolization on disease-free survival after hepatectomy for hepatocellular carcinoma.
- Author:
Zhijian ZHANG
1
;
Mengchao WU
;
Han CHEN
;
Jiamei YANG
;
Guangshun YANG
;
Feng SHEN
;
Jia HE
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Aged; Carcinoma, Hepatocellular; surgery; therapy; Catheterization; Child; Disease-Free Survival; Embolization, Therapeutic; Female; Hepatectomy; Hepatic Artery; Humans; Liver Neoplasms; surgery; therapy; Male; Middle Aged; Postoperative Care; Retrospective Studies
- From: Chinese Journal of Surgery 2002;40(5):329-331
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate postoperative transcatheter hepatic arterial chemoembolization (TACE) for improving the disease-free survival of HCC patients after hepatectomy.
METHODS1 725 HCC patients were followed up after hepatectomy retrospectively. Of 1 457 patients who were followed-up completely, 209 had postoperative TACE. The 1 457 patients were divided into ten groups according to tumor thrombus, small HCC, capsular invasion, vascular invasion and cirrhosis. The disease-free survival was analyzed between subgroups of weather postoperative TACE was performed in every group. Software SAS 6.12 and EGRET package were used. Kaplan-Meier estimation was used to calculate the disease-free survival rates.
RESULTSThere were no difference of the disease-free survival between the subgroups in no capsular invasion and in no hepatic cirrhosis groups.
CONCLUSIONPostoperative TACE is helpful in improving the disease-free survival of HCC patients after hepatectomy except those with integrated tumor envelope or no hepatocirrhosis. It is important to prolong the long-term results of operation.