Value of computed tomography features for prognosis evaluation of gastrointestinal stromal tumor.
- Author:
Zhen-peng PENG
1
;
Can-hui SUN
;
Yan-ji LUO
;
Zhi DONG
;
Xue-hua LI
;
Zi-ping LI
;
Shi-ting FENG
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Female; Follow-Up Studies; Gastrointestinal Neoplasms; diagnostic imaging; Gastrointestinal Stromal Tumors; diagnostic imaging; Humans; Male; Middle Aged; Prognosis; Survival Rate; Tomography, X-Ray Computed; methods
- From: Chinese Journal of Gastrointestinal Surgery 2013;16(3):230-233
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo analyze the association between CT features and survival rate of GIST, and to elucidate the significance of CT features for prognosis.
METHODSClinical data of 38 patients with pathologically and immunohistochemically proven GISTs, including 11 patients at high biological risk, 13 at moderate risk, 10 at low risk and 4 at very low risk. Patients who underwent CT examination for primary tumors were included. Association between CT features and survival rate was examined.
RESULTSThe mean follow-up period of 38 cases was 42.6 months and the 3-year survival rate was 86.8%. Univariate analysis revealed that tumor growth pattern, diameter, lobulated shape, irregular margin, necrosis, ulceration, adjacent invasion, and liver metastasis were associated factors of 3-year survival rate. Circumference invasion and hepatic metastases predicted poor 3-year survival rate (P<0.05). Calcification and intensity were not associated with prognosis (P>0.05).
CONCLUSIONSCT can demonstrate the tumor growth pattern, size, shape, boundary, density, necrosis, hemorrhage, calcification, ulcer, enhance features and metastasis. CT can play an important role in estimating the survival rate of GIST.
