Brain mappings in non-fluent late Chinese-English bilinguals.
- Author:
Han GAO
1
;
Hong-min BAI
;
Li-xin HAN
;
Tian-dong LI
;
Wei WANG
;
Yi-bing LIU
;
Jian LIN
;
Xuan ZENG
;
Guo-liang WANG
;
Yu-bao WANG
;
Li-min WANG
;
Xiao-peng ZHANG
;
Wei-min WANG
2
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Brain Mapping; Brain Neoplasms; surgery; Cerebral Cortex; physiology; Female; Humans; Magnetic Resonance Imaging; Male; Multilingualism; Young Adult
- From: Chinese Journal of Surgery 2013;51(11):1021-1024
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo discuss the distribution characteristics of language areas in Chinese-English non-fluent late bilinguals.
METHODSSix Chinese-English bilinguals with eloquent tumors underwent awake-surgeries. The activated areas of BOLD-fMRI were obtained as the patients performed pure naming, verb generation, and abstract/concrete judgment tasks. Direct cortical stimulation(DCS) as the golden standard of language mapping were performed during awake-surgeries on the exposed cortical areas. BOLD-fMRI results of 3 language tasks were compared with DCS results. The statistical method was McNemer.
RESULTSSixteen positive sites(22.5%) were comfirmed out of 71 stimulations. There were 3 specific language sites, in which 2 sites were specific English sites and 1 site was specific Chinese site. When activated areas of BOLD-fMRI were compared with the DCS results, verb generation task had the highest concordance rate 40.9% (95%CI:30.2%-52.5%) . There were significant differences between the results of BOLD-fMRI and DCS of all 3 bilingual tasks(P < 0.017).
CONCLUSIONSThere are specific language areas in Chinese-English non-fluent late bilinguals. The BOLD-fMRI language mapping could not substitute DCS in the context of mapping language areas in bilinguals.