Detection of bladder cancer by narrow band imaging cystoscopy: a meta-analysis.
- Author:
Bo XIONG
1
;
Changjian ZHENG
1
;
Chengguo ZHANG
1
;
Wei WEI
1
;
Yarong WANG
1
;
Jun LUO
1
;
Hongmei YANG
1
;
Hongzhi WANG
2
Author Information
- Publication Type:Journal Article
- MeSH: Cystoscopy; methods; Humans; Narrow Band Imaging; Sensitivity and Specificity; Urinary Bladder Neoplasms; diagnosis
- From: Chinese Journal of Surgery 2014;52(4):289-293
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVESTo evaluate the value of narrow band imaging (NBI) cystoscopy in detection of bladder cancer.
METHODSLiteratures on narrow-band imaging cystoscopy in diagnosis of bladder cancer, controlled clinical research was searched in PubMed, Cochrane Library,EMbase, and the Chinese Biomedical Literature Database. The literatures were selected according to the inclusion and exclusion criteria. The Meta-DiSc 1.4 software was used to review management and analysis.
RESULTSThe 8 studies met the inclusion criteria. On a per-people analysis, the pooled sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, diagnostic odds ratio (DOR) of NBI cystoscopy and white light imaging (WLI) cystoscopy were respectively 0.943 (95%CI: 0.914-0.964) and 0.848 (95%CI: 0.803- 0.885), 0.847 (95%CI: 0.812-0.878) and 0.870 (95%CI: 0.831-0.903), 7.038 (95%CI: 3.357-14.754) and 6.938 (95%CI: 2.052-23.465), 0.054 (95%CI: 0.012-0.237) and 0.181 (95%CI: 0.091-0.361), 185.32 (95%CI: 45.714-751.260) and 42.931 (95%CI: 8.088-227.880). The areas under the curve (AUC) and Q* of NBI cystoscopy and WLI cystoscopy were 0.978 and 0.894, 0.934 and 0.825 respectively.
CONCLUSIONNBI cystoscopy is accurate with high diagnostic precision for diagnosis of bladder cancer. NBI cystoscopy is prior to WLI cystoscopy, but it needs more clinical evidence for further affirmance.
