Regulative effect of traditional Chinese medicine on gene-expression related to precancerous lesion of gastric cancer.
- Author:
Fang-shi ZHU
1
;
Jian-min SI
Author Information
1. Zhejiang University, Sir Run Run Shaw Hospital of College Medicine, Hangzhou, China. zhufs@tom.com
- Publication Type:Journal Article
- MeSH:
Animals;
Apoptosis;
genetics;
Gene Expression;
Humans;
Medicine, Chinese Traditional;
Oncogenes;
Precancerous Conditions;
genetics;
Stomach Neoplasms
- From:Chinese journal of integrative medicine
2005;11(1):76-80
- CountryChina
- Language:English
-
Abstract:
The gene-expression changes related with precancerous lesion of gastric cancer (PLGC) are surveyed. Not only the regulative effect of traditional Chinese medicine (TCM) on oncogene, antioncogene and anti-apoptosis gene that are related with PLGC is analyzed, but also current research state is presented. It's showed that TCM has effects of therapy and inversion on PLGC. These effects are related with the inhibition to related oncogene expression, the regulation and activation to the deletion of antioncogene, the inhibition to the high-expression of mutant gene-protein about antioncogene, and the regulative function to anti-apoptosis gene.
