Comparative observation on the effects of Radix tripterygium hypoglaucum tablet and Tripterygium glycosides tablet in treating erosive oral lichen planus.
- Author:
Li-mei LIN
1
;
Xiang-min QI
Author Information
- Publication Type:Clinical Trial
- MeSH: Adult; Aged; Drugs, Chinese Herbal; administration & dosage; adverse effects; Female; Glycosides; administration & dosage; adverse effects; Humans; Lichen Planus, Oral; drug therapy; Male; Middle Aged; Treatment Outcome; Tripterygium
- From: Chinese journal of integrative medicine 2005;11(2):149-150
- CountryChina
- Language:English
-
Abstract:
OBJECTIVETo compare the therapeutic effects of Radix Tripterygium hypoglaucum tablet (THT) and Tripterygium glycosides tablet (TGT) in treating erosive oral lichen planus (EOLP).
METHODSThe patients were randomized into two groups, and they were treated with THT (n = 47) or TGT (n = 47), respectively. The therapeutic effects were evaluated after 3 months treatment.
RESULTSFor the patients of grade 1, the total efficacy in TGT group was 85.71%, compared with 52.38% in THT group, the efficacy was statistically greater in the group receiving TGT (P = 0.043). However, for the patients of grade 2, the difference was not statistically significant (P = 0.173).
CONCLUSIONTGT is more effective in treating EOLP than THT for grade 1 patients. However, TGT is not suitable for patients of child bearing age.
