The more efficacious acupoints of Zusanli and Sanyinjiao than that of non-acupoints on bone mass in osteopenic ovariectomized rats.
- Author:
Wen-ping ZHANG
1
;
Masayuki KANEHARA
;
Yan-jun ZHANG
;
Zhi-feng YU
;
Guo-xia ZHANG
;
You-xin YANG
;
Yu-min SUN
;
Jian-mei ZHANG
;
Torao ISHIDA
Author Information
- Publication Type:Journal Article
- MeSH: Acupuncture Points; Animals; Bone Density; Bone Diseases, Metabolic; prevention & control; Female; Ovariectomy; Rats; Rats, Sprague-Dawley
- From:Chinese journal of integrative medicine 2005;11(3):209-216
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo clarify whether the acupoints of Zusanli (ST36) and Sanyinjiao (SP6) have specific actions other than non-acupoints to bone.
METHODSForty Sprague-Dawley female rats were divided into five groups: Sham operated (sham) group; Ovariectomized (OVX, model) group; non-acupuncture group; OVX, needling on Zusanli and Sanyinjiao (Acp-A) group; OVX, needling on the reverse sides of Zusanli and Sanyinjiao (Acp-B) group; OVX, periostineal stimulation on the same height as points of Zusanli and Sanyinjiao (Acp-C) group. The experiment was continued for 23 weeks and then all animals were sacrificed.
RESULTSOVX had a significantly higher body weight and lower bone mineral density (BMD) on the lumbar vertebrae, total femora and tibiae than sham rats, however, Acp-A showed a higher BMD compared with the other OVX groups. On the other hand, bone weights, bone strength and bone morphometry such as trabecular volume, trabecular separation, labeled width and bone formation rate also showed the same improvements in Acp-A as compared to the other OVX rats.
CONCLUSIONThe stimulation on Zusanli and Sanyinjiao specifically prevented the development of osteopenic rats compared with non-acupoints.
