Correlation analysis of magnetic resonance imaging characteristics and intrahepatic recurrence of small hepatocellular carcinoma after radiofrequency ablation.
- VernacularTitle:小肝癌射频消融治疗前后磁共振成像表现及其与肿瘤肝内复发的相关性
- Author:
Ruofan SHENG
1
,
2
,
3
;
Zhenggang REN
;
Lan ZHANG
;
Caizhong CHEN
;
Mengsu ZENG
Author Information
- Publication Type:Journal Article
- MeSH: Carcinoma, Hepatocellular; pathology; Catheter Ablation; Humans; Kaplan-Meier Estimate; Liver Neoplasms; pathology; Magnetic Resonance Imaging; Recurrence; Retrospective Studies; Survival Rate; Treatment Outcome
- From: Chinese Journal of Hepatology 2014;22(9):680-685
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the correlation between magnetic resonance imaging (MRI) characteristics and intrahepatic recurrence of small hepatocellular carcinoma (HCC) after radiofrequency ablation (RFA).
METHODSA total of 34 patients with 39 small HCC who underwent RFA were included in our study.MRI characteristics were compared between the recurrence group and the non-recurrence group; and a subgroup comparison was also made between the solitary recurrence group and the multiple recurrence group.Kaplan-Meier test,t-test/Mann-Whitney U test,Fisher's exact test and F-test were used for statistical analyses.
RESULTSThe median follow-up period was 25 (4-45) months and recurrence was observed in 19 (55.9%) of the patients.The 12-and 24-month cumulative recurrence-free survival rates were 71.3% and 51.8%,respectively.The recurrence group had a higher prevalence of lack of tumour capsule before RFA (P =0.017),no or disrupted periablational enhancement within 24 hours after RFA (P =0.012),and a smaller ablative margin (P=0.037).Meanwhile,the average apparent diffusion coefficient value within 24 hours after RFA was higher in the multiple recurrence group (1.57 * 10-3mm2/s) than in the solitary recurrence group (1.34 * 10(-3) mm2/s) (P =0.04).
CONCLUSIONMRI can provide early noninvasive findings useful for advanced warning ofintrahepatic recurrence after RFA.
